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Location & approach

By car

The campus of TU Dortmund University is located close to interstate junction Dortmund West, where the Sauerlandlinie A 45 (Frankfurt-Dortmund) crosses the Ruhrschnellweg B 1 / A 40. The best interstate exits to take from A 45 is “Dortmund-Eichlinghofen” (closer to South Campus), and from B 1 / A 40 “Dortmund-Dorstfeld” or “Dortmund-Barop” (both closer to North Campus). Signs to the university are located at all the exits.

To get from North Campus to South Campus by car, there is the connection via Vogelpothsweg/Baroper Straße. We recommend you leave your car on one of the parking lots at North Campus and use the H-Bahn (suspended monorail system), which conveniently connects the two campuses.

By train

TU Dortmund University has its own train station (“Dortmund Universität”). From there, suburban trains (S-Bahn) leave for Dortmund main station (“Dortmund Hauptbahnhof”) and Düsseldorf main station via the “Düsseldorf Airport Train Station” (take S-Bahn number 1, which leaves every 15 or 30 minutes). The university is easily reached from Bochum, Essen, Mülheim an der Ruhr and Duisburg.

You can also take the bus or subway train from Dortmund city to the university: From Dortmund main station, you can take any train bound for the Station “Stadtgarten”, usually lines U41, U45, U 47 and U49. At “Stadtgarten” you switch trains and get on line U42 towards “Hombruch”. Look out for the Station “An der Palmweide”. From the bus stop just across the road, busses bound for TU Dortmund University leave every ten minutes (445, 447 and 462). Another option is to take the subway routes U41, U45, U47 and U49 from Dortmund main station to the stop “Dortmund Kampstraße”. From there, take U43 or U44 to the stop “Dortmund Wittener Straße”. Switch to bus line 447 and get off at “Dortmund Universität S”.

By plane

The AirportExpress is a fast and convenient means of transport from Dortmund Airport (DTM) to Dortmund Central Station, taking you there in little more than 20 minutes. From Dortmund Central Station, you can continue to the university campus by interurban railway (S-Bahn). A larger range of international flight connections is offered at Düsseldorf Airport (DUS), which is about 60 kilometres away and can be directly reached by S-Bahn from the university station.

H-Bahn

The H-Bahn (Suspended Monorail System) is one of the hallmarks of TU Dortmund University. There are two stations on North Campus. One (“Dortmund Universität S”) is directly located at the suburban train stop, which connects the university directly with the city of Dortmund and the rest of the Ruhr Area. Also from this station, there are connections to the “Technologiepark” and (via South Campus) Eichlinghofen. The other station is located at the dining hall at North Campus and offers a direct connection to South Campus every five minutes.

Plan of site & interactive map

The facilities of TU Dortmund University are spread over two campuses, the larger Campus North and the smaller Campus South. Additionally, some areas of the university are located in the adjacent "Technologiepark".

> Go to interactive map

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Cafeteria menus

To overview

Location & approach

By car

The campus of TU Dortmund University is located close to interstate junction Dortmund West, where the Sauerlandlinie A 45 (Frankfurt-Dortmund) crosses the Ruhrschnellweg B 1 / A 40. The best interstate exits to take from A 45 is “Dortmund-Eichlinghofen” (closer to South Campus), and from B 1 / A 40 “Dortmund-Dorstfeld” or “Dortmund-Barop” (both closer to North Campus). Signs to the university are located at all the exits.

To get from North Campus to South Campus by car, there is the connection via Vogelpothsweg/Baroper Straße. We recommend you leave your car on one of the parking lots at North Campus and use the H-Bahn (suspended monorail system), which conveniently connects the two campuses.

By train

TU Dortmund University has its own train station (“Dortmund Universität”). From there, suburban trains (S-Bahn) leave for Dortmund main station (“Dortmund Hauptbahnhof”) and Düsseldorf main station via the “Düsseldorf Airport Train Station” (take S-Bahn number 1, which leaves every 15 or 30 minutes). The university is easily reached from Bochum, Essen, Mülheim an der Ruhr and Duisburg.

You can also take the bus or subway train from Dortmund city to the university: From Dortmund main station, you can take any train bound for the Station “Stadtgarten”, usually lines U41, U45, U 47 and U49. At “Stadtgarten” you switch trains and get on line U42 towards “Hombruch”. Look out for the Station “An der Palmweide”. From the bus stop just across the road, busses bound for TU Dortmund University leave every ten minutes (445, 447 and 462). Another option is to take the subway routes U41, U45, U47 and U49 from Dortmund main station to the stop “Dortmund Kampstraße”. From there, take U43 or U44 to the stop “Dortmund Wittener Straße”. Switch to bus line 447 and get off at “Dortmund Universität S”.

By plane

The AirportExpress is a fast and convenient means of transport from Dortmund Airport (DTM) to Dortmund Central Station, taking you there in little more than 20 minutes. From Dortmund Central Station, you can continue to the university campus by interurban railway (S-Bahn). A larger range of international flight connections is offered at Düsseldorf Airport (DUS), which is about 60 kilometres away and can be directly reached by S-Bahn from the university station.

H-Bahn

The H-Bahn (Suspended Monorail System) is one of the hallmarks of TU Dortmund University. There are two stations on North Campus. One (“Dortmund Universität S”) is directly located at the suburban train stop, which connects the university directly with the city of Dortmund and the rest of the Ruhr Area. Also from this station, there are connections to the “Technologiepark” and (via South Campus) Eichlinghofen. The other station is located at the dining hall at North Campus and offers a direct connection to South Campus every five minutes.

Plan of site & interactive map

The facilities of TU Dortmund University are spread over two campuses, the larger Campus North and the smaller Campus South. Additionally, some areas of the university are located in the adjacent "Technologiepark".

> Go to interactive map

ServicePortal UniMail

Veröffentlichung in renommiertem Fachjournal

Forschungsteam entschlüsselt dynamische Regulation von Zellbewegungen

12/02/2020 -

in

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Dr. Leif Dehmelt stands in a laboratory — Dr. Leif Dehmelt ist Privatdozent an der Fakultät für Chemie und Chemische Biologie der TU Dortmund und Forschungsgruppenleiter am Max-Planck-Institut für molekulare Physiologie.

Viele Zellen im menschlichen Körper sind ständig in Bewegung. Das ist wichtig, um zum Beispiel Entzündungen bekämpfen zu können, und elementar für die Embryonalentwicklung. Auch Krebszellen machen sich diese Bewegungen zu eigen. Dr. Leif Dehmelt, Privatdozent an der Fakultät für Chemie und Chemische Biologie der TU Dortmund und Forschungsgruppenleiter am Max-Planck-Institut für molekulare Physiologie, hat gemeinsam mit einem internationalen Team mithilfe einer lichtbasierten Technik regulatorische Signalnetzwerke entschlüsselt, welche die Zellbewegungen kontrollieren. Die Ergebnisse wurden nun in der renommierten Fachzeitschrift Cell Reports veröffentlicht.

Einzelne Körperzellen erzeugen sehr dynamische Kontraktionen, wodurch sie ständig ihre Form ändern und in Bewegung sind. So können beispielsweise weiße Blutkörperchen an der Innenseite der Blutgefäße entlangwandern und von dort durch winzige Zwischenräume zu Entzündungsherden gelangen, um diese zu bekämpfen. Ähnlich verhält es sich mit Krebszellen, die in fremdes Gewebe eindringen und dort Metastasen bilden. Ein besseres Verständnis dafür, wie sich Zellen bewegen und wie sich ihre Signalnetzwerke unter bestimmten Bedingungen verhalten, kann dabei helfen, die Ausbreitung von Krebszellen oder Fehlbildungen bei Embryonen besser nachzuvollziehen und neue, zielgerichtete Therapien zu entwickeln.

Um das Signalnetzwerk, das die Zellkontraktion steuert, zu untersuchen, hat Dehmelts Gruppe gezielt spezielle Moleküle, deren Funktion mit blauem Licht gesteuert werden kann, in lebende Zellen eingebracht. Mithilfe dieser Lichtkontrolle konnte sie unter dem Mikroskop Veränderungen der Netzwerkdynamik in den Zellen beobachten und messen. Aus dieser optogenetischen Untersuchung konnte sie Rückschlüsse auf die Signalverarbeitung ziehen: Ein zentraler Aspekt sind insbesondere positive und negative Rückkopplungsschleifen im Netzwerk, welche dynamische Signalpulse erzeugen.